Horizon Europe 2025 work programme Cluster 1: Health

Topics available under Horizon Europe’s Health programme for 2025/26, with funding of up to €20m per project.

Opportunity Details

When

Registration Opens

03/05/2025

Registration Closes

16/09/2025

Award

The indicative amount of EU funding contributions for most projects ranges from €2m to €20m. This can cover up to 100% of costs depending on the call.

Organisation

Horizon Europe

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Read the Horizon Europe 2025 work programmes

The European Commission has pre-published all of the 2025 Horizon Europe Work Programmes, which list the funding opportunities under the 2025 call topics.

No matter your field – whether you’re a business, university, research institute, charity, or not-for-profit – you could be eligible to apply for Horizon Europe funding to advance your cutting-edge research and innovation, fostering lasting impact and meaningful change.

Our Innovate UK European Team and UK National Contact Points can support you with these exciting potential funding opportunities and help you get the most out of Horizon Europe.

UK organisations are usually eligible to take part in Horizon Europe actions (as part of a three-organisation consortium; see “Who can apply?” below). Our teams can help you to find collaboration partners.

The available topics in Cluster 1, Health, are summarised below; for 2025, they have been subdivided into 6 Destinations. For further details on each call, visit the Horizon Europe list of work programmes for 2025, and also sign up for the Brokerage Days (5-6 May) and Info Day (22 May) below.

Closing dates are 3 Jun 2025 for two Partnerships in Health calls (both under Tackling Diseases), and 16 Sep 2025 for all other calls. For two-stage calls, the second stage closing date is 16 Apr 2026.

  • Unless otherwise provided for in the specific call/topic conditions, only legal entities forming a consortium are eligible to participate in actions provided that the consortium includes, as beneficiaries, three legal entities independent from each other and each established in a different country as follows:

    • at least one independent legal entity established in a Member State;
    • and at least two other independent legal entities, each established in different Member States or Associated Countries (this includes the UK).

    Our European team can help you find eligible partners to form a consortium.

    There may be further eligibility conditions for specific topics. Please check the Work Programme and talk to our team to ensure your eligibility before applying.

  • The online Brokerage event (5-6 May 2025, 10am-7pm CET/9am-6pm GMT) will be dedicated to consortium building in Cluster 1 Health.

    The Brokerage event is organised before the Cluster 1 Health Info Day (22 May, 9am CET/8am GMT) in order to give potential applicants more time to find potential partners and prepare their application.

    Register for the Brokerage Days, 5-6 May

    Register for the Info Day, 22 May

  • There is only one topic for this destination: “Improving the quality of life of persons with intellectual disabilities and their families”. The total indicative budget is €40m, with an expected contribution of €6-8m per project and an indicative expectation of 5 projects.

    This is a two-stage call, opening 22 May 2025, with a first stage deadline of 16 Sep 2025 and second stage deadline of 16 Apr 2026.

  • Topics available:

    The impact of pollution on the development and progression of brain diseases and disorders (budget €40m, c. €6-7m per project). Two stage call, first deadline 16 Sep 2025, final deadline 16 Apr 2026.

    Advancing knowledge on the impacts of micro- and nanoplastics on human health (budget €40m, c. €7-8m per project). Two stage call, first deadline 16 Sep 2025, final deadline 16 Apr 2026.

  • Topics available:

    Testing safety and efficacy of phage therapy for the treatment of antibiotic-resistant bacterial infections (€45m total budget, c.€15m per project): single stage, deadline 16 Sep 2025

    Advancing innovative interventions for mental, behavioural and neurodevelopmental disorders (budget €50m, c. €6-8m per project). Two stage call, first deadline 16 Sep 2025, final deadline 16 Apr 2026.

    Development of antibodies and antibody-derived proteins for the prevention and treatment of infectious diseases with epidemic potential (€50m total budget, c.€10m per project): single stage, deadline 16 Sep 2025

    Leveraging artificial intelligence for pandemic preparedness and response (€35m total budget, c.€6-8m per project): single stage, deadline 16 Sep 2025

    Support for the functioning of the Global Research Collaboration for Infectious Disease Preparedness (GloPID-R) (€2m total budget to fund one project): single stage, deadline 16 Sep 2025

    Implementation research addressing strategies to strengthen health systems for equitable high-quality care and health outcomes in the context of non-communicable diseases (GACD) (€20m total budget, c.€3-4m per project): single stage, deadline 16 Sep 2025

    Tackling high-burden for patients and underresearched medical conditions (€30m total budget, c.€6m per project): single stage, deadline 16 Sep 2025

    European Partnership for Brain Health (€150m total budget for a single 3-year project – part of the Partnerships in Health Call, opening 13 May 2025, deadline 3 June 2025)

    European partnership fostering a European Research Area (ERA) for health research (Phase 2) (€77m total budget for a single project – part of the Partnerships in Health Call, opening 13 May 2025, deadline 3 June 2025)

  • There is only one topic in this destination: End-user-driven application of Generative Artificial Intelligence models in healthcare (GenAI4EU) (€40m total budget, c.€15-20m per project): single stage, deadline 16 Sep 2025.

  • Topics available:

    Enhancing cell therapies with genomic techniques (€50m total budget, c.€8-10m per project): single stage, deadline 16 Sep 2025

    Advancing cell secretome-based therapies (€40m total budget, c.€9-13m per project): single stage, deadline 16 Sep 2025

    Leveraging multimodal data to advance Generative Artificial Intelligence applicability in biomedical research (GenAI4EU) (€50m total budget, c.€15-17m per project): single stage, deadline 16 Sep 2025

    Boosting the translation of biotech research into innovative health therapies (€80m total budget, c.€4-8m per project): single stage, deadline 16 Sep 2025

  • Topics available:

    Optimising the manufacturing of Advanced Therapy Medicinal Products (ATMPs) (€40m total budget, c.€6-8m per project): single stage, deadline 16 Sep 2025

    Digitalisation of conformity assessment procedures of medical devices and in vitro diagnostic medical devices (€4m total budget for a single project): single stage, deadline 16 Sep 2025

    Facilitating the conduct of multinational clinical studies of orphan devices and/or of highly innovative (“breakthrough”) devices (budget €0m, c. €6-8m per project). Two stage call, first deadline 16 Sep 2025, final deadline 16 Apr 2026.

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