Horizon Europe 2025 work programme Cluster 1: Health

Unless otherwise provided for in the specific call/topic conditions, only legal entities forming a consortium are eligible to participate in Horizon Europe actions provided that the consortium includes, as beneficiaries, three legal entities independent from each other and each established in a different country as follows:

• at least one independent legal entity established in a Member State;
• and at least two other independent legal entities, each established in different Member States or Associated Countries (this includes the UK).

Our European team can help you find eligible partners to form a consortium.

There may be further eligibility conditions for specific topics. Please check the Work Programme and contact our team to ensure your eligibility before applying.

The online Brokerage event (5-6 May 2025, 10am-7pm CET/9am-6pm GMT) will be dedicated to consortium building in Cluster 1 Health.

The Brokerage event is organised before the Cluster 1 Health Info Day (22 May, 9am CET/8am GMT) in order to give potential applicants more time to find potential partners and prepare their application.

Register for the Brokerage Days, 5-6 May

Register for the Info Day, 22 May

Health researchers working in cancer-related areas may also wish to sign up for the EU Missions Info Days including the Cancer Mission on 23 May, and related Brokerage Events on 26-27 May.

There is only one topic for this destination: “Improving the quality of life of persons with intellectual disabilities and their families”. The total indicative budget is €40m, with an expected contribution of €6-8m per project and an indicative expectation of 5 projects. This is a two-stage call, opening 22 May 2025, with a first stage deadline of 16 Sep 2025 and second stage deadline of 16 Apr 2026.

Topics available: both two stage calls, first deadline 16 Sep 2025, final deadline 16 Apr 2026.

• The impact of pollution on the development and progression of brain diseases and disorders (budget €40m, c. €6-7m per project).
• Advancing knowledge on the impacts of micro- and nanoplastics on human health (budget €40m, c. €7-8m per project). 

Topics available (note early deadlines for the first two!):

European Partnership for Brain Health (€150m total budget for a single 3-year project – part of the Partnerships in Health Call, opening 13 May 2025, deadline 3 June 2025)

European partnership fostering a European Research Area (ERA) for health research (Phase 2) (€77m total budget for a single project – part of the Partnerships in Health Call, opening 13 May 2025, deadline 3 June 2025)

Advancing innovative interventions for mental, behavioural and neurodevelopmental disorders (budget €50m, c. €6-8m per project). Two stage call, first deadline 16 Sep 2025, final deadline 16 Apr 2026.

All remaining calls in this destination are single-stage with a deadline of 16 Sep 2025:

• Testing safety and efficacy of phage therapy for the treatment of antibiotic-resistant bacterial infections (€45m total budget, c.€15m per project)
• Development of antibodies and antibody-derived proteins for the prevention and treatment of infectious diseases with epidemic potential (€50m total budget, c.€10m per project)
• Leveraging artificial intelligence for pandemic preparedness and response (€35m total budget, c.€6-8m per project)
• Support for the functioning of the Global Research Collaboration for Infectious Disease Preparedness (GloPID-R) (€2m total budget to fund one project)
• Implementation research addressing strategies to strengthen health systems for equitable high-quality care and health outcomes in the context of non-communicable diseases (GACD) (€20m total budget, c.€3-4m per project)
• Tackling high-burden for patients and underresearched medical conditions (€30m total budget, c.€6m per project)

There is only one topic in this destination: End-user-driven application of Generative Artificial Intelligence models in healthcare (GenAI4EU) (€40m total budget, c.€15-20m per project): single stage, deadline 16 Sep 2025.

Topics available, all single stage calls with deadline 16 Sep 2025:

• Enhancing cell therapies with genomic techniques (€50m total budget, c.€8-10m per project)
• Advancing cell secretome-based therapies (€40m total budget, c.€9-13m per project)
• Leveraging multimodal data to advance Generative Artificial Intelligence applicability in biomedical research (GenAI4EU) (€50m total budget, c.€15-17m per project)
• Boosting the translation of biotech research into innovative health therapies (€80m total budget, c.€4-8m per project)

Topics available:

Optimising the manufacturing of Advanced Therapy Medicinal Products (ATMPs) (€40m total budget, c.€6-8m per project): single stage, deadline 16 Sep 2025

Digitalisation of conformity assessment procedures of medical devices and in vitro diagnostic medical devices (€4m total budget for a single project): single stage, deadline 16 Sep 2025

Facilitating the conduct of multinational clinical studies of orphan devices and/or of highly innovative (“breakthrough”) devices (budget €0m, c. €6-8m per project). Two stage call, first deadline 16 Sep 2025, final deadline 16 Apr 2026.